Overview

SCIENTIFIC SCORE
Questionable
Based on 13 Researches
6.9
USERS' SCORE
Good
Based on 31 Reviews
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopheryl Acetate) 
268 mg 
1787%

Top Medical Research Studies

9
Vitamin E reduces menstrual pain
We investigated whether vitamin E could help with primary dysmenorrhea, a common cause of pelvic pain for young women. In our study, 278 girls aged 15-17 took either vitamin E or a placebo before and during their menstrual periods.

Results showed that those taking vitamin E experienced significantly less pain and shorter pain duration compared to the placebo group. There was also a notable reduction in menstrual blood loss. This suggests that vitamin E may be a beneficial option for managing menstrual discomfort.
Read More
8
Vitamin E may reduce dysmenorrhea pain
In a double-blind clinical trial, we examined the impact of vitamin E on pelvic pain for 120 women suffering from primary dysmenorrhea. Participants were divided into two groups, with one receiving daily doses of 400 IU of vitamin E, while the other group received a placebo.

Our findings showed that both groups reported reduced pain; however, those taking vitamin E experienced a more significant drop in pain severity. This indicates that vitamin E could be a safe and effective option for treating menstrual pain in women.
Read More
8
Vitamin E offers menstrual pain relief
We explored how effective vitamin E is in treating primary dysmenorrhoea through a randomized placebo-controlled trial. In this study, 100 girls aged 16-18 were divided into two groups; one received 500 units of vitamin E daily, while the other took a placebo.

Treatment started two days before menstruation and continued for three days. Both groups experienced relief from pain, but those taking vitamin E reported more significant improvements.

This suggests that while both treatments help, vitamin E may offer an added benefit in managing menstrual pain.
Read More

Most Useful Reviews

7.5
Reduced pelvic pain
35 people found this helpful
Rejuvenating vitamins! I have suffered from pelvic pain linked to PMS and heavy menstrual bleeding for years. After following advice on Professor Fujikawa's blog to take vitamins C, E, D3, K2, and magnesium, I've noticed a significant reduction in my symptoms. My irritability before the period has improved, and the excessive bleeding has decreased. This has made my menstruation far more manageable!
Read More
10
Eliminated pelvic pain
30 people found this helpful
I’ve struggled with intense pelvic pain during my periods but after taking this supplement for about three months, the pain has completely disappeared! Initially, the pain was softer, but now I can manage my period comfortably without disruption. I will continue taking it.
Read More
9
No pelvic pain
14 people found this helpful
After reading a doctor's book on protein and megavitamins, I began taking vitamin E about six months ago, and since then, my pelvic pain and PMS have nearly vanished. Prior to this, I only took vitamin E and noticed no benefits, but adding it to my regimen made all the difference. Before, I felt extremely low before my period.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 13 Researches
6.9
  • All Researches
9
Vitamin C and E reduce pelvic pain
We examined the effects of vitamin C and E on pelvic pain in women with endometriosis through a triple-blind, placebo-controlled trial. Sixty women aged 15-45 participated, receiving either the vitamin combination or a placebo daily for eight weeks.

Our results revealed noteworthy decreases in pelvic pain, dysmenorrhea, and dyspareunia for those who took vitamins, supporting their potential in managing endometriosis symptoms. While oxidative stress markers showed changes, total antioxidant capacity did not significantly decline.
Read More
9
Vitamin E reduces menstrual pain
We investigated whether vitamin E could help with primary dysmenorrhea, a common cause of pelvic pain for young women. In our study, 278 girls aged 15-17 took either vitamin E or a placebo before and during their menstrual periods.

Results showed that those taking vitamin E experienced significantly less pain and shorter pain duration compared to the placebo group. There was also a notable reduction in menstrual blood loss. This suggests that vitamin E may be a beneficial option for managing menstrual discomfort.
Read More
8
Vitamin E supports pelvic pain relief
We explored the impact of antioxidants, specifically vitamins C and E, on pelvic pain associated with endometriosis. Analyzing data from five randomized controlled trials, we found that patients receiving vitamin supplementation reported significant reductions in chronic pelvic pain, dysmenorrhea, and dyspareunia compared to those on placebo.

This suggests that these vitamins may play a beneficial role in alleviating symptoms for those suffering from endometriosis-related pain. Overall, antioxidant supplementation presents a promising avenue for management of this challenging condition.
Read More
8
Vitamin E shows limited effectiveness
We examined how antioxidant vitamins, including vitamin E, may help reduce pelvic pain related to endometriosis. Our systematic review analyzed studies that used randomized controlled trials, focusing on pain scores assessed by the Visual Analogue Scale.

While the findings suggest that vitamin E supplementation might lower pain severity and improve overall well-being, the evidence does not conclusively support significant benefits for all individuals.

However, these antioxidants could still be considered as part of a comprehensive approach to manage pelvic pain associated with endometriosis.
Read More
8
Vitamin E may reduce dysmenorrhea pain
In a double-blind clinical trial, we examined the impact of vitamin E on pelvic pain for 120 women suffering from primary dysmenorrhea. Participants were divided into two groups, with one receiving daily doses of 400 IU of vitamin E, while the other group received a placebo.

Our findings showed that both groups reported reduced pain; however, those taking vitamin E experienced a more significant drop in pain severity. This indicates that vitamin E could be a safe and effective option for treating menstrual pain in women.
Read More

User Reviews

USERS' SCORE
Good
Based on 31 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Reduced pelvic pain
35 people found this helpful
Rejuvenating vitamins! I have suffered from pelvic pain linked to PMS and heavy menstrual bleeding for years. After following advice on Professor Fujikawa's blog to take vitamins C, E, D3, K2, and magnesium, I've noticed a significant reduction in my symptoms. My irritability before the period has improved, and the excessive bleeding has decreased. This has made my menstruation far more manageable!
Read More
10
Eliminated pelvic pain
30 people found this helpful
I’ve struggled with intense pelvic pain during my periods but after taking this supplement for about three months, the pain has completely disappeared! Initially, the pain was softer, but now I can manage my period comfortably without disruption. I will continue taking it.
Read More
9
No pelvic pain
14 people found this helpful
After reading a doctor's book on protein and megavitamins, I began taking vitamin E about six months ago, and since then, my pelvic pain and PMS have nearly vanished. Prior to this, I only took vitamin E and noticed no benefits, but adding it to my regimen made all the difference. Before, I felt extremely low before my period.
Read More
10
Alleviated pelvic pain
9 people found this helpful
I bought this for my daughter, who endured severe pelvic pain during her periods. Since starting this supplement, she no longer experiences the debilitating pain that interrupted her school attendance. The soft gel form makes it easy to consume without an unpleasant taste, making it a great option for anyone suffering from severe menstrual pain.
Read More
10
Improved migraines
8 people found this helpful
Since hearing that vitamin E can relieve headaches and pelvic pain, it has become essential for my family. Previously, we relied on painkillers, but now vitamin E helps us avoid medication. My children no longer complain about headaches, and they improve significantly within an hour when I take a few pills. I ensure to take it with some oily food for best results.
Read More

Frequently Asked Questions

10
Eliminated pelvic pain
30 people found this helpful
I’ve struggled with intense pelvic pain during my periods but after taking this supplement for about three months, the pain has completely disappeared! Initially, the pain was softer, but now I can manage my period comfortably without disruption. I will continue taking it.
9
No pelvic pain
14 people found this helpful
After reading a doctor's book on protein and megavitamins, I began taking vitamin E about six months ago, and since then, my pelvic pain and PMS have nearly vanished. Prior to this, I only took vitamin E and noticed no benefits, but adding it to my regimen made all the difference. Before, I felt extremely low before my period.
7.5
Eased pelvic pain
7 people found this helpful
After experiencing intense postpartum pelvic pain and heavy bleeding, I started taking 800 IU of vitamin E daily. My next period was much easier, and I noticed a significant reduction in both bleeding and pain, allowing me to avoid medication and feel more at ease. I recommend starting with a lower dosage initially.
10
Alleviated pelvic pain
9 people found this helpful
I bought this for my daughter, who endured severe pelvic pain during her periods. Since starting this supplement, she no longer experiences the debilitating pain that interrupted her school attendance. The soft gel form makes it easy to consume without an unpleasant taste, making it a great option for anyone suffering from severe menstrual pain.
7.5
Reduced pelvic pain
35 people found this helpful
Rejuvenating vitamins! I have suffered from pelvic pain linked to PMS and heavy menstrual bleeding for years. After following advice on Professor Fujikawa's blog to take vitamins C, E, D3, K2, and magnesium, I've noticed a significant reduction in my symptoms. My irritability before the period has improved, and the excessive bleeding has decreased. This has made my menstruation far more manageable!
9
No more pain
3 people found this helpful
Natural vitamin E (d-α-tocopherol) improves nutrient uptake and has made a noticeable difference for me. Since taking it along with vitamin C, I’ve experienced almost no PMS or pelvic pain, and I can now live comfortably throughout each month.
10
Pain-free periods
7 people found this helpful
This supplement, taken with protein, has nearly eliminated my pelvic pain. The capsule is easy to swallow, and it’s also useful for improving rough skin when applied topically. It’s a natural tocopherol and I highly recommend it.
8
Vitamin E supports pelvic pain relief
We explored the impact of antioxidants, specifically vitamins C and E, on pelvic pain associated with endometriosis. Analyzing data from five randomized controlled trials, we found that patients receiving vitamin supplementation reported significant reductions in chronic pelvic pain, dysmenorrhea, and dyspareunia compared to those on placebo.

This suggests that these vitamins may play a beneficial role in alleviating symptoms for those suffering from endometriosis-related pain. Overall, antioxidant supplementation presents a promising avenue for management of this challenging condition.
9
Vitamin C and E reduce pelvic pain
We examined the effects of vitamin C and E on pelvic pain in women with endometriosis through a triple-blind, placebo-controlled trial. Sixty women aged 15-45 participated, receiving either the vitamin combination or a placebo daily for eight weeks.

Our results revealed noteworthy decreases in pelvic pain, dysmenorrhea, and dyspareunia for those who took vitamins, supporting their potential in managing endometriosis symptoms. While oxidative stress markers showed changes, total antioxidant capacity did not significantly decline.
8
Vitamin E shows limited effectiveness
We examined how antioxidant vitamins, including vitamin E, may help reduce pelvic pain related to endometriosis. Our systematic review analyzed studies that used randomized controlled trials, focusing on pain scores assessed by the Visual Analogue Scale.

While the findings suggest that vitamin E supplementation might lower pain severity and improve overall well-being, the evidence does not conclusively support significant benefits for all individuals.

However, these antioxidants could still be considered as part of a comprehensive approach to manage pelvic pain associated with endometriosis.
We examined the effects of vitamin E on primary dysmenorrhea, which causes painful menstrual cramps. In a systematic review, we analyzed randomized controlled trials comparing vitamin E supplementation to placebo in healthy women.

Although vitamin E may help reduce pain intensity for some women, the evidence is not strong enough yet. We recommend more robust clinical trials to provide clearer insights on its effectiveness.
We reviewed several studies to see how dietary supplements, including vitamin E, affect painful menstrual cramps, known as dysmenorrhoea.

In our analysis of 27 trials with over 3,100 women, we found that vitamin E showed no significant benefit in reducing pain. Most evidence for all supplements was rated low quality due to small participant numbers and inconsistent findings.

Overall, while some supplements had hints of effectiveness, none were conclusively beneficial, and further research is needed to explore their potential.
8
Vitamin E may reduce dysmenorrhea pain
In a double-blind clinical trial, we examined the impact of vitamin E on pelvic pain for 120 women suffering from primary dysmenorrhea. Participants were divided into two groups, with one receiving daily doses of 400 IU of vitamin E, while the other group received a placebo.

Our findings showed that both groups reported reduced pain; however, those taking vitamin E experienced a more significant drop in pain severity. This indicates that vitamin E could be a safe and effective option for treating menstrual pain in women.

References

  1. Bayu P, Wibisono JJ. Vitamin C and E antioxidant supplementation may significantly reduce pain symptoms in endometriosis: A systematic review and meta-analysis of randomized controlled trials. PLoS One. 2024;19:e0301867. doi:10.1371/journal.pone.0301867
  2. Zheng SH, Chen XX, Chen Y, Wu ZC, Chen XQ, et al. Antioxidant vitamins supplementation reduce endometriosis related pelvic pain in humans: a systematic review and meta-analysis. Reprod Biol Endocrinol. 2023;21:79. doi:10.1186/s12958-023-01126-1
  3. Alikamali M, Mohammad-Alizadeh-Charandabi S, Maghalian M, Mirghafourvand M. The effects of vitamin E on the intensity of primary dysmenorrhea: A systematic review and meta-analysis. Clin Nutr ESPEN. 2022;52:50. doi:10.1016/j.clnesp.2022.10.001
  4. Amini L, Chekini R, Nateghi MR, Haghani H, Jamialahmadi T, et al. The Effect of Combined Vitamin C and Vitamin E Supplementation on Oxidative Stress Markers in Women with Endometriosis: A Randomized, Triple-Blind Placebo-Controlled Clinical Trial. Pain Res Manag. 2021;2021:5529741. doi:10.1155/2021/5529741
  5. Orimadegun BE, Awolude OA, Agbedana EO. Markers of lipid and protein peroxidation among Nigerian university students with dysmenorrhea. Niger J Clin Pract. 2019;22:174. doi:10.4103/njcp.njcp_279_18
  6. Sadeghi N, Paknezhad F, Rashidi Nooshabadi M, Kavianpour M, Jafari Rad S, et al. Vitamin E and fish oil, separately or in combination, on treatment of primary dysmenorrhea: a double-blind, randomized clinical trial. Gynecol Endocrinol. 2018;34:804. doi:10.1080/09513590.2018.1450377
  7. Pattanittum P, Kunyanone N, Brown J, Sangkomkamhang US, Barnes J, et al. Dietary supplements for dysmenorrhoea. Cochrane Database Syst Rev. 2016;3:CD002124. doi:10.1002/14651858.CD002124.pub2
  8. Ray K, Fahrmann J, Mitchell B, Paul D, King H, et al. Oxidation-sensitive nociception involved in endometriosis-associated pain. Pain. 2015;156:528. doi:10.1097/01.j.pain.0000460321.72396.88
  9. Kashanian M, Lakeh MM, Ghasemi A, Noori S. Evaluation of the effect of vitamin E on pelvic pain reduction in women suffering from primary dysmenorrhea. J Reprod Med. 2013;58:34.
  10. Santanam N, Kavtaradze N, Murphy A, Dominguez C, Parthasarathy S. Antioxidant supplementation reduces endometriosis-related pelvic pain in humans. Transl Res. 2013;161:189. doi:10.1016/j.trsl.2012.05.001
  11. Ziaei S, Zakeri M, Kazemnejad A. A randomised controlled trial of vitamin E in the treatment of primary dysmenorrhoea. BJOG. 2005;112:466.
  12. Ziaei S, Faghihzadeh S, Sohrabvand F, Lamyian M, Emamgholy T. A randomised placebo-controlled trial to determine the effect of vitamin E in treatment of primary dysmenorrhoea. BJOG. 2001;108:1181.
  13. Kryzhanovskiĭ GN, Bakuleva LP, Luzina NL, Vinogradov VA, Iarygin KN. [Endogenous opioid system in the realization of the analgesic effect of alpha-tocopherol in reference to algomenorrhea]. Biull Eksp Biol Med. 1988;105:148.
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